최신 ASM-ABMM ABMM 무료샘플문제:
1. A clinical microbiology laboratory is using isothermal nucleic acid amplification techniques for rapid detection of Mycobacterium tuberculosis in sputum. Compared to conventional PCR, isothermal methods offer the advantage of:
A) The ability to simultaneously amplify multiple targets in a single reaction.
B) Higher sensitivity and specificity for detecting low levels of target DNA.
C) Easier integration with downstream analysis techniques such as Sanger sequencing.
D) Faster reaction times and the ability to be performed without sophisticated thermocyclers.
2. A microbiology laboratory receives a corneal scraping from a patient with keratitis. Microscopic examination with calcofluor white stain reveals the presence of septate hyphae and conidiophores with a foot cell and phialides. The MOST likely genus is:
A) Rhizopus
B) Candida
C) Mucor
D) Aspergillus
3. A clinical microbiology laboratory encounters a Gram-negative bacillus isolated from a bloodstream infection. The isolate exhibits resistance to multiple antibiotics, including carbapenems. Further phenotypic testing reveals the production of a metallo-beta-lactamase (MBL). Which of the following antibiotic combinations might still retain activity against this isolate?
A) Aztreonam-avibactam
B) Aztreonam
C) Piperacillin-tazobactam
D) Ceftazidime-avibactam
4. A researcher is studying the genetic relatedness of different isolates of Mycobacterium tuberculosis. Which of the following molecular typing methods provides the highest discriminatory power for distinguishing between closely related strains?
A) Restriction fragment length polymorphism (RFLP) analysis
B) Whole-genome sequencing (WGS)
C) Spoligotyping
D) Pulsed-field gel electrophoresis (PFGE)
5. A clinical microbiology laboratory is using Sanger sequencing to identify mutations associated with antibiotic resistance in Mycobacterium tuberculosis. This method directly determines the:
A) Relative abundance of different M. tuberculosis strains in a mixed infection.
B) Presence or absence of specific resistance genes.
C) Minimum inhibitory concentration (MIC) of the antibiotic.
D) Nucleotide sequence of the target gene.
질문과 대답:
질문 # 1 정답: D | 질문 # 2 정답: D | 질문 # 3 정답: B | 질문 # 4 정답: B | 질문 # 5 정답: D |